Transdermal patches are just another way of delivering medication to the bloodstream. Patients with lupus often respond to cannabis. It relieves pain and anxiety, and is mood elevating. With a transdermal patch, there is a more even delivery of medicine over an extended period of time. The medicine enters the bloodstream so if there is only THC, you may experience it's intoxicating effects as well. Many companies produce patches with both CBD and THC. What I recommend for all autoimmune patients is CBD. CBD modulates the autoimmune system and is a potent anti-inflammatory. THC adds to its pain-relieving benefits and helps alleviate depression. As with any delivery method, start with a small dose and gradually increase it until your symptoms respond.