I would recommend a CBD:THC ratio of 20:1 twice daily every day for chronic inflammation/cancer if you need to function and cannot be "high". You must increase the dose as tolerated. Another option is Rick Simpson Oil which makes you "high" and is more intense. Generally patients finish a 60g tube of oil orally over 3 months by starting with a 1/2 a rice grain size oil droplet on a piece of toast to start once daily. Hope this helps!