I have terrible IBS and want to know if CBD may help with intestinal issues?

"I’m not interested in being high, but someone told me that CBD may be able to help me."


There is far more reason to try CBD than not to. There are interesting laboratory science reports showing possible ways it may be helpful, and anecdotal reports of benefit in IBS, along with virtually no reports of adverse effects. You may find through experimentation that varying the CBD:THC ratio of the preparation you are using may lead you to the most beneficial formula for your symptoms. Good luck.

drelkind


Hello,
Activating cannabinoid receptors has been shown to inhibit gastrointestinal fluid secretion and inflammation in animal models. Several studies indicate that cannabinoids in marijuana bind with cannabinoid receptors in the digestive tract, especially the small and large intestine.

Furthermore, both CBD and THC have been shown to reduce the inflammatory response in patients with autoimmune diseases, such as multiple sclerosis, lupus and celiac disease; both CBD and THC have also been shown to help alleviate pain.

"CBD may interact at extra-cannabinoid system receptor sites, such as peroxisome proliferator-activated receptor-gamma. This strategic interaction makes CBD as a potential candidate for the development of a new class of anti-IBD drugs."
https://www.ncbi.nlm.nih.gov/pubmed/22815234

"CBD targets enteric reactive gliosis, counteracts the inflammatory environment … in human colonic cultures derived from UC patients. These actions lead to a reduction of intestinal damage. Our results therefore indicate that CBD indeed unravels a new therapeutic strategy to treat inflammatory bowel diseases."
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028159

drkim

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