"I'm sick and tired of taking antihistamines."
Scientists in Germany have discovered that applying THC ointment or solutions to the skin of mice and then exposing them to allergens resulted in decreased inflammation and swelling when compared to non-treated mice.
It appears that activating the CB-1 and CB-2 receptors (main cannabinoid receptors) reduces the symptoms caused by plants that produce hypersensitivity rashes similar to poison ivy or poison oak.
There is limited literature available on this topic but, allergy and hypersensitivity to cannabis is rare.
Additionally, Cannabis shares some molecular and other characteristics with antihistamines which we use to treat allergies.
Further study needs to be done before we can say definitively that cannabis helps with allergies, but these initial findings may lead to more work in this area.