Any advice for using CBD for helping to improve Hashimotos? What’s the recommended daily dose?

"I’ve seen vapour devices, are these more superior in delivery than liquid drops"


Hi there!

In a 2015 cross sectional analysis study designed to assess the relationship between marijuana and thyroid function, researchers found that "cannabis had a weak but statistically significant inverse correlation between recent marijuana use and the thyroid antibodies TPOAb and TBGAb, while free T3 showed a significant positive correlation." Or, in other words, cannabis use correlated to decreased levels of thyroid-attacking antibodies, and higher levels of T3, suggesting that recent cannabis use improved thyroid function via reducing thyroid autoimmunity — several studies have demonstrated cannabis’ immunomodulatory  properties — and either a direct or indirect positive effect on T3 levels.
http://abstracts.eurospe.org/hrp/0084/hrp0084P3-1183

In a similar study, researchers "showed that recent marijuana users had significantly lower frequency of elevated thyrotropin (TSH) and positive anti-thyroperoxidase antibody (TPOAb) versus nonusers/past users."
https://www.ncbi.nlm.nih.gov/pubmed/27799014

drkim


Furthermore, in a 2009 preclinical study, researchers found that the type 1 cannabinoid receptor 1 (CB1) was densely present on both excitatory and inhibitory inputs on TRH (thyroid releasing hormone) neurons, suggesting that the endocannabinoid system may help regulate the appropriate manufacturing and secretion of the thyroid hormones, T3 and T4. This also makes sense, since the endocannabinoid system (ECS) is largely devoted to maintaining homeostasis (the tendency of organisms to auto-regulate and maintain their internal environment at equilibrium).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630898

As of yet, there are no clinical studies evaluating CBD’s or THC’s specific effects on thyroid function. However, I would hypothesize that CBD would reduce the body’s self-attack on the thyroid/ reduce circulating thyroid antibodies, but would have less, if any, of a direct effect on the manufacturing and secretion of thyroid hormone. CBD has been shown to have profound immunomodulatory properties. However, CBD does not meaningfully interact with the CB1 receptor, and thus, would not directly affect thryroid releasing hormone neurons in the method described in the above 2009 study.

drkim


As far as dosage goes: In general, I would recommend between 10 and 20 milligrams of CBD twice per day.
For Hashimoto’s (and most chronic conditions without acute symptoms) I generally recommend an oil or edible over inhalation methods.

https://www.hellolift.com/products/5b57b4c702f1740001523089/cured-full-spectrum-raw-oil
contains about 0.83mg of CBD/drop: take 12 drops (10mg) to 23 drops (20mg) twice/day.

https://www.hellolift.com/products/5b57a71f02f1740001522f78/cbd-hemp-oil-capsules
1 pill (15mg) twice per day.

Please consult with your physician before starting any cannabis regimen. Do not discontinue your thyroid medication before consulting with your prescribing physician.

drkim

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